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Indian J Exp Biol ; 2007 Jul; 45(7): 649-53
Article in English | IMSEAR | ID: sea-61810

ABSTRACT

Significant increase in polyamines levels in inflamed tissue was observed in the experimental animal models of inflammation. Treatment with dexamethasone positively modulated the levels of polyamines whereas non-steroidal drugs, diclofenac and valdecoxib negatively modulated their levels.


Subject(s)
Animals , Anti-Inflammatory Agents/chemistry , Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Carrageenan/pharmacology , Cell Proliferation , Cyclooxygenase Inhibitors/pharmacology , Dexamethasone/pharmacology , Diclofenac/pharmacology , Drug Interactions , Inflammation , Isoxazoles/chemistry , Polyamines/chemistry , Rats , Rats, Wistar , Steroids/chemistry , Sulfonamides/chemistry
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